TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed)
A1  - Nellessen, Cornelius
A1  - Klein, Thomas
A1  - Rapp, Hans-Jürgen
A1  - Rögener, Frank
T1  - Membrane Distillation for the Production of Pharmaceutical-Grade Water—Investigation into the Application of AGMD and VMD
JF  - International Journal of Environmental Research and Public Health
N2  - The production of pharmaceutical ingredients, intermediates and final products strongly depends on the utilization of water. Water is also required for the purification and preparation of reagents. Each specific application determines the respective water quality. In the European Union, the European Pharmacopeia (Ph. Eur.) contains the official standards that assure quality control of pharmaceutical products during their life cycle. According to this, the production of water for pharmaceutical use is mainly based on multi-stage distillation and membrane processes, especially, reverse osmosis. Membrane distillation (MD) could be an alternative process to these classical methods. It offers advantages in terms of energy demand and a compact apparatus design. In the following study, the preparation of pharmaceutical-grade water from tap water in a one-step process using MD is presented. Special emphasis is placed on the performance of two different module designs and on the selection of optimum process parameters.
KW  - Wasser
KW  - Membrane Distillation
KW  - Pharmaceutical-Grade Water
KW  - Pure Water
KW  - AGMD
KW  - VMD
Y1  - 2021
UN  - https://nbn-resolving.org/urn:nbn:de:hbz:832-epub4-17092
SN  - 1660-4601
SS  - 1660-4601
U6  - https://doi.org/10.3390/ijerph18116058
DO  - https://doi.org/10.3390/ijerph18116058
VL  - 18
IS  - 11
SP  - 18
S1  - 18
PB  - MDPI
ER  -