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Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry

  • A fiber-based linear optical coherence tomography (LOCT) system employing a cost-effective CMOS camera has previously demonstrated high-resolution imaging suitable for retinal screening, including glaucoma monitoring. However, the system’s imaging depth was constrained to approximately 400μm, insufficient for depth imaging of the optic nerve head (ONH), due to limitations imposed by the camera’s sensor size and pixel pitch. To overcome this limitation without replacing the economical and available sensor, we present a modification to the reference arm. By optimizing the utilization of the camera sensor’s vertical dimension, the system achieves an extended imaging depth, enabling the visualization of deeper tissue structures. Validation using an artificial eye model confirms that the modified LOCT system significantly enhances imaging depth while maintaining B-Scan quality. This advancement offers a cost-effective approach to extend the measurement range of LOCT systems, broadening their applicability in retinal imaging without altering the actual imaging sensor.
Metadaten
Author:Niklas Bauer, David Harings, Damian Mendroch, Jan Matrisch, Uwe Oberheide, Alexander Heisterkamp
URN:urn:nbn:de:hbz:832-epub4-29740
DOI:https://doi.org/10.1117/12.3046633
Parent Title (English):Ophthalmic Technologies XXXV : Proceedings Volume 13300 / Hammer, Daniel X.; Nankivil, Derek; Tao, Yuankai K. (Hrsg.). - SPIE Photonics West; San Francisco, California, United States; 25-31 January 2025 - In: Proceedings of SPIE : The International Society for Optical Engineering - SPIE
Descirption of the primary publication:SPIE, Proceedings Volume 13300, Ophthalmic Technologies XXXV; 133000I (2025) https://doi.org/10.1117/12.3046633
Document Type:Preprint
Language:English
Date of Publication (online):2025/05/16
GND-Keyword:Interferometrie; Optische Kohärenztomografie
Tag:Interferometry; LOCT; OCT; Retinal Imaging
Page Number:7
Institutes:Informations-, Medien- und Elektrotechnik (F07) / Fakultät 07 / Institut für Angewandte Optik und Elektronik
Dewey Decimal Classification:500 Naturwissenschaften und Mathematik / 530 Physik
600 Technik, Medizin, angewandte Wissenschaften / 610 Medizin, Gesundheit
Open Access:Open Access
Licence (German):License LogoCreative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International