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Learning more about the ways in which market participants in the reinsurance market interact based on the logic of a game requires a realisation that the main research that exists is in the mathematical/actuarial direction in which mathematicians deal with ‘optimal reinsurance contracts’. In this connection, negotiations between cedants and reinsurers are viewed in different ways, but always as a strategic game.
This thesis is aimed for finding a solution for non-gaming application of Virtual Reality technology in data visualization and analysis. Starting by reconstructing the concept of Virtual Reality, the paper then describes the principles, concepts and techniques of designing a Virtual Reality application. In the last part of the thesis, a detailed description of how a prototype implemented is presented to provide a preview of how data visualization and analysis and Virtual Reality technology can be combined together in order to enable users to perceive and comprehend data in a possibly better way.
With Google’s Flutter framework continuing to grow in popularity for companies and developers alike, the need for an understanding of how to utilize the framework in a large-scale context has become more relevant than ever. The purpose of this thesis is to document the crucial steps most development teams using Flutter in a large-scale application will face. Additionally, a fully documented, large-scale reference application was generated so that other developers may use it as an aid when creating their own Flutter projects on a similar scale. Multiple steps were taken to ensure that optimal solutions were chosen for each aspect of the development process. For each of those aspects, a wide range of possible solutions were explored, compared and analysed. Finally, one of the possible solutions was chosen based on a wide range of scientific papers and community-generated sources. Additionally, an interview with an expert in the field was conducted to further validate those decisions. After the application was fully implemented, ten crucial aspects of the development process were identified. Those ten aspects are now explained in detail in this thesis. Ultimately, the knowledge provided by this thesis can act as a map for peers using Flutter in a large-scale context and help them overcome the crossroads they will most likely come to face.
The method of operation of auctions and their use in
a variety of economic sectors is already well documented. Auctions are already in use for the Placement of reinsurance on a small scale. So why is it important to revisit
this field, which has already been studied in such considerable detail?
• Two researchers, Paul R. Milgrom and Robert B. Wilson of Stanford University, were honoured with the Nobel Prize in Economics in 2020 for their improvements in auction theory and the invention of new auction formats.
• A trend towards automation is in the Placement of reinsurance is emerging. In this connection, a variety of InsurTechs and market initiatives, such as B3i and
Ritablock, are dealing with various fields of application of blockchain technology.
• The persistent low-interest-rate environment, together with existing competition
and cost pressures from primary insurers, mean that insurers are in search of savings potentials.
• Auctions are proving to be a successful model in many areas of the economy, e.g. in the allocation of frequencies in mobile communication, subsidies for wind farms or energy pricing.
Achieving urban water security is a major challenge for many countries. While several studies have assessed water security at a regional level, many studies have also emphasized the lack of assessment of water security and application of measures to achieve it at the urban level.
Recent studies that have focused on measuring urban water security are not holistic, and there is still no agreed-upon understanding of how to operationalize and identify an assessment framework to measure the current state and dynamics of water security. At present, there is also no clearly defined and widely endorsed definition of urban water security. To address this challenge, this study provides a systematic approach to better understand urban water security, with a working definition and an assessment framework to be applied in peri-urban and urban areas. The proposed working definition of urban water security is based on the United Nations (UN) sustainable development goal on water and sanitation and the human rights on water and sanitation. It captures issues of urban-level technical, environmental, and socio-economic indicators that emphasize credibility, legitimacy, and salience.
The assessment framework depends on four main dimensions to achieve urban water security: Drinking water and human beings, ecosystem, climate change and water-related hazards, and socio-economic factors (DECS). The framework further enables the analysis of relationships and trade-off between urbanization and water security, as well as between DECS indicators. Applying this framework will help governments, policy-makers, and water stakeholders to target scant resources more eff ectively and sustainably. The study reveals that achieving urban water security requires a holistic and integrated approach with collaborative stakeholders to provide a meaningful way to improve understanding and managing urban water security.
Circular economy (CE) has received considerable interest in recent years as a strategy to resolve some of our modern urban resource challenges, and circular city models often incorporate systems of urban agriculture in their design. Much work has analyzed the benefits of urban agriculture for creating a resilient food system and as a strategy for supporting urban green space and social cohesion, however, the contributions from business models that operate within urban agriculture have not been thoroughly studied. Many urban agriculture businesses often claim high levels of resource recycling and material circularity, though whether a resource efficiency throughout the entire product lifetime (including energy and material footprint for the cultivation equipment) in comparison to current industrial strategies is truly feasible or even possible is still to be debated. This thesis builds upon work that incorporates social dimensions of CE definitions and begins to research whether the potential resource efficiency contradiction can be justified as to make urban agriculture a valid approach for circular city design. This study examined an urban mushroom farm that implements a circular business model. A qualitative summary of the business operations and resource flows were unpacked and sorted into 24 socio-economic contributions based on their interpreted relevance. The interpreted data shows that an urban agriculture business model can contribute to the building blocks of a CE through economic, ecological, social, and spatial contributions. While these contributions can contribute positively to the operationalization of CE, potential trade-offs regarding resource efficiency, use of urban space, and investment priorities need to be considered and addressed to avoid a possible watering down or greenwashing of the CE concept.
In recent years, three sovereign catastrophe risk pools have developed worldwide, offering climate insurance against natural disasters in emerging and developing economies:
• Caribbean Catastrophe Risk Insurance Facility (CCRIF) in the Caribbean
• African Risk Capacity (ARC) in Africa
• Pacific Catastrophe Risk Insurance Company (PCRIC) in the Pacific region
These pools have emerged against the backdrop of limited fiscal room for manoeuvre in emerging and developing economies. Increases in tax revenues or capital allocations are scarcely possible in these economies. Moreover, debt on the capital market often ends in debt relief, and this can jeopardise refinancing. Ultimately, the only measure remaining is to provide donations and aid that can be made available by the G7 countries, the World Bank or the World Health Organization, among others.
Stable recombinant mammalian cells are of growing importance in pharmaceutical biotechnology production scenarios for biologics such as monoclonal antibodies, growth and blood factors, cytokines and subunit vaccines. However, the establishment of recombinant producer cells using classical stable transfection of plasmid DNA is hampered by low stable gene transfer efficiencies. Consequently, subsequent selection of transgenic cells and the screening of clonal cell populations are time- and thus cost-intensive. To overcome these limitations, expression cassettes were embedded into transposon-derived donor vectors. Upon the co-transfection with transposase-encoding constructs, elevated vector copy numbers stably integrated into the genomes of the host cells are readily achieved facilitating under stringent selection pressure the establishment of cell pools characterized by sustained and high-yield recombinant protein production. Here, we discuss some aspects of transposon vector technologies, which render these vectors promising candidates for their further utilization in the production of biologics.
In this paper we describe traffic sign recognition with neural networks in the frequency domain. Traffic signs exist in all countries to regulate the traffic of vehicles and pedestrians. Each country has its own set of traffic signs that are more or less similar. They consist of a set of abstract forms, symbols, numbers and letters, which are combined into different signs. Automatic traffic sign recognition is important for driver assistance systems and for autonomous driving. Traffic sign recognition is a subtype of image recognition. The traffic signs are usually recorded by a camera and must be recognized in real time, i.e. assigned to a class. We use neural networks for traffic sign recognition. The special feature of our method is that the traffic sign recognition does not take place in the spatial domain but in the frequency domain. This has advantages because it is possible to significantly reduce the number of neurons and thus the computing effort of the neural network compared to a conventional neural network.
Despite intensive research over the last three decades, it has not yet been possible to bring an effective vaccine against human immunodeficiency virus (HIV) and the resulting acquired immunodeficiency syndrome (AIDS) to market. Virus-like particles (VLP) are a promising approach for efficient and effective vaccination and could play an important role in the fight against HIV. For example, HEK293 (human embryo kidney) cells can be used to produce virus-like particles. In this context, given the quality-by-design (QbD) concept for manufacturing, a digital twin is of great importance for the production of HIV-Gag-formed VLPs. In this work, a dynamic metabolic model for the production of HIV-Gag VLPs was developed and validated. The model can represent the VLP production as well as the consumption or formation of all important substrates and metabolites. Thus, in combination with already described process analytical technology (PAT) methods, the final step towards the implementation of a digital twin for process development and design, as well as process automation, was completed.
Usage of smart home solutions implies generation, processing, and storage of machine and personal data. Recently made public cases of data breaches and misuse increased peoples’ concerns of data security and decreased the trust in secure data handling and smart home technologies. Hence potential benefits are not exploited. It is therefore necessary to analyse how manufacturers can increase their online trust perception.
Requirements of (potential) customers of web based services for HVAC systems are identified using thematic analysis for 23 conducted interviews using online trust perception literature as basis. Manufacturer independent websites are derived as the most important online touch point for customers with manufacturers and products. Determined content and structure measures for online touch points managed by manufacturers derived to positively influence the manufacturer and manufacturer independent touch points regarding perception of trust. The derived trust concept must be evaluated in the following using the defined evaluation plan.
Abstract
Due to their pronounced bioactivity and limited availability from natural resources, metabolites of the soft coral Pseudopterogorgia elisabethae, such as erogorgiaene and the pseudopterosines, represent important target molecules for chemical synthesis. We have now developed a particularly short and efficient route towards these marine diterpenes exploiting an operationally convenient enantioselective cobalt‐catalyzed hydrovinylation as the chirogenic step. Other noteworthy C−C bond forming transformations include diastereoselective Lewis acid‐mediated cyclizations, a Suzuki coupling and a carbonyl ene reaction. Starting from 4‐methyl‐styrene the anti‐tubercular agent (+)‐erogorgiaene (>98 % ee) was prepared in only 7 steps with 46 % overall yield. In addition, the synthesis of the pseudopterosin A aglycone was achieved in 12 steps with 30 % overall yield and, surprisingly, was found to exhibit a similar anti‐inflammatory activity (inhibition of LPS‐induced NF‐κB activation) as a natural mixture of pseudopterosins A−D or iso‐pseudopterosin A, prepared by β‐D‐xylosylation of the synthetic aglycone.
Aerobic microbial cultivations are industrially important group of processes and pose challenges for the reactor design. In particular, estimation of industrial scale conditions is difficult from laboratory and pilot scale data. Due to complex interaction of gas/liquid phase hydrodynamics, mass transfer parameters and microbial metabolism, both improvement of modelling tools and reactor design are desired. We present an approach to estimate growth conditions in industrial scale reactor by combining black-box metabolic models with CFD-model.
The reactor type used here is Outotec OKTOP9000®, which is used in the industrial hydrometallurgical processes at 900 m3 scale. It is adopted to a laboratory setting and compared to stirred tank reactor (STR) in gas dispersion, mass transfer and yeast cultivation experiments. In addition, a kinetic model for the yeast growth is developed based on literature sources and validated by the laboratory scale batch cultivations. This kinetic model is used along with CFD-model that is developed to describe the flow and mass transfer conditions in the industrial scale reactor.
The laboratory scale experiments show the feasibility of OKTOP9000® reactor when compared to STR, particularly with improved gas handling capacity. The modelling approach shows qualitatively similar behavior in the large scale simulations when compared to laboratory scale cultivations.
Thioredoxin (Trx) overexpression is known to be a cause of chemotherapy resistance in various tumor entities. However, Trx effects on resistance are complex and depend strictly on tissue type. In the present study, we analyzed the impact of the Trx system on intrinsic chemoresistance of human glioblastoma multiforme (GBM) cells to cytostatic drugs. Resistance of GBM cell lines and primary cells to drugs and signaling inhibitors was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays. Impact of Trx inhibition on apoptosis was investigated by proteome profiling of a subset of proteins and annexin V apoptosis assays. Trx-interacting protein (TXNIP) was overexpressed by transfection and protein expression was determined by immunoblotting. Pharmacological inhibition of Trx by 1-methyl-2-imidazolyl-disulfide (PX-12) reduced viability of three GBM cell lines, induced expression of active caspase-3, and reduced phosphorylation of AKT-kinase and expression of β-catenin. Sensitivity to cisplatin could be restored by both PX-12 and recombinant expression of the upstream Trx inhibitor TXNIP, respectively.
In addition, PX-12 also sensitized primary human GBM cells to temozolomide. Combined inhibition of Trx and the phosphatidylinositide 3-kinase (PI3K) pathway resulted in massive cell death. We conclude that the Trx system and the PI3K pathway act as a sequential cascade and could potentially present a new drug target.
AbstractThis paper discusses the comparison of two methods to achieve thermal comfort utilising air conditioning (AC) system in a small indoor space – adaptive control and fuzzy control. Thermal comfort indoors is performed to provide comfortability individually or for a group of people. Due to the small indoor space which usually a bit cramped, crowded and less airy, the ambience can be very uncomfortable either for doing sedentary or active work, thus the AC system can be very useful to provide thermal comfort. Both methods can be utilised depending on how thermal comfort is viewed and how the level of thermal comfort is decided. Every method has its own advantage and limitations, and will be covered in this paper as well.
On 25 May 2011, the OECD launched a "Green Growth Strategy" and proposed a "Green Growth Diagnostics" approach to identify the binding constraints on green growth. This paper discusses the potential use and usefulness of this approach as a means to identify those binding constraints. It is argued that the approach is best used at the meso level for industries and certain environmental challenges. The paper proposes a modified green growth diagnostics approach for eco-innovations at the meso level that can be useful for informing and organising a rational policy dialogue amongst all stakeholders.
This paper documents the design, implementation and evaluation of the Unfolding Space Glove—an open source sensory substitution device. It transmits the relative position and distance of nearby objects as vibratory stimuli to the back of the hand and thus enables blind people to haptically explore the depth of their surrounding space, assisting with navigation tasks such as object recognition and wayfinding. The prototype requires no external hardware, is highly portable, operates in all lighting conditions, and provides continuous and immediate feedback—all while being visually unobtrusive. Both blind (n = 8) and blindfolded sighted participants (n = 6) completed structured training and obstacle courses with both the prototype and a white long cane to allow performance comparisons to be drawn between them. The subjects quickly learned how to use the glove and successfully completed all of the trials, though still being slower with it than with the cane. Qualitative interviews revealed a high level of usability and user experience. Overall, the results indicate the general processability of spatial information through sensory substitution using haptic, vibrotactile interfaces. Further research would be required to evaluate the prototype’s capabilities after extensive training and to derive a fully functional navigation aid from its features.
We examine the impact of the existence on an explicit deposit insurance (DI) scheme and its design features on bilateral cross‐border deposits (CBD) in a gravity model setting. We find that both the absolute quality of a country's DI and its relative quality vis‐à‐vis other countries' DI generally affect depositor behavior. However, during systemic banking crises, cross‐border depositors primarily seek countries with the best DI schemes. Similarly, during the 2008–2009 great financial crisis, the emergency actions taken by the governments, which supply and maintain these safe havens, have led to substantial relocations of CBD. (JEL F34, G18)
This thesis analyzes the history and current circumstances women belonging to ethnic minorities find themselves in. It also examines how social work deals with this issue. The situation of Indigenous women in Canada as well as Sinti and Roma women in Germany will serve as an example. Within Germany, there are no comparable Indigenous groups that went through a history similar to that of the Indigenous people of Canada. Thus, within the realms of possibility, it is intended to compare their situation to that of Sinti and Roma women and their communities in Germany. After comparing both groups and their current situation, possible consequences and improvements for the field of social work will be indicated
The southeast of Córdoba province used to be originally covered by hundreds of wetlands that got heavily modified or drained in the last few decades. Since wetlands provide various important ecosystem services (ESS) for human well-being, their degradation created several problems in La Picasa basin, among which floods are the most obvious one. The wise use of wetlands is increasingly acknowledged to be part of nature-based solution approaches reducing disaster risk. However, in the study area these approaches remain a relatively new concept to decision makers and the lack of knowledge on their effectiveness and implementation process poses a serious barrier to their adoption.
To overcome this obstacle, this dissertation applies an ESS perspective on the current problems of La Picasa basin and sets it in a context of socio-ecological system (SES) theory. A comprehensive analysis of (1) the role wetlands have played in the historic development of the SES, (2) important stakeholder dynamics that create opportunities or restrictions for the conservation of wetlands and (3) possible management approaches to inverse negative ESS trade-offs and feedback loops, was performed.
Results demonstrate that the current problems of floods have both natural and anthropogenic causes. In this regard, wetlands hold a vital role in the complex historic interactions between the social and ecological drivers of changes in the water balance. Although a social network between stakeholders exists, several conflicts prevent a proper functioning of a basin-wide integrated management concept based on wetland restoration. Nature-based solution approaches, putting wetlands in the center of attention of future management strategies, were found to hold a high potential to reduce the risk of floods and, as a side-effect boost biodiversity and habitat quality in the study area.
Wetlands offer different ecosystem services that contribute to human well-being (Kovács et al., 2015). According to the Ramsar Convention Secretariat (2018) wetland located in urban areas have been threatened by several activities such as drainage, pollution, encroachment, agriculture, among others. On the other hand, wetland degradation reduces the resilience of hazards like floods and storm surges (Kumar et al., 2017). For that reason, ecosystem-based disaster risk reduction (Eco-DRR) is an important strategy which enhances the conservation and restoration of ecosystems to reduce disaster risk aiming to sustainable development and resilience (Estrella & Saalismaa, 2013). Despite international recognition of the importance of wetlands, urban wetlands have diminished their capacity to cope with flood threats (Boyer and Polasky, 2006) due to the aforementioned human impacts.
That is why this thesis aimed to identify the role of urban wetlands in Bogota, Colombia, that has an urban wetland complex that is recognised as a Ramsar site in 2018. However, wetlands in the city reduced its area from 50.000 hectares to less than 800, approximately, in less than 40 years, mainly because of urban expansion and encroachment (IDIGER, 2018). To achieve this objective, an analysis of the city’s risk management framework was conducted, as well as a stakeholder analysis based on semi-structured interviews and a spatial-temporal analysis for the period 1998-2017, for which the Jaboque wetland was used as a case study. This wetland is located near the Bogotá River and is in the area threatened by flooding.
It was possible to determine that national and district policies on wetlands, biodiversity, and climate change adaptation address some ecosystem functions. Still, disaster risk reduction is not strongly linked to them. Thus, based on the case study, the wetlands in Bogota have not played a decisive role in flood risk management in the city.
This study aimed to simulate the sector-coupled energy system of Germany in 2030 with the restriction on CO2 emission levels and to observe how the system evolves with decreasing emissions. Moreover, the study presented an analysis of the interconnection between electricity, heat and hydrogen and how technologies providing flexibility will react when restricting CO2 emissions levels. This investigation has not yet been carried out with the technologies under consideration in this study. It shows how the energy system behaves under different set boundaries of CO2 emissions and how the costs and technologies change with different emission levels. The study results show that the installed capacities of renewable technologies constantly increase with higher limitations on emissions. However, their usage rates decreases with low CO2 emission levels in response to higher curtailed energy. The sector-coupled technologies behave differently in this regard. Heat pumps show similar behaviour, while the electrolysers usage rate increases with more renewable energy penetration. The system flexibility is not primarily driven by the hydrogen sector, but in low CO2 emission level scenarios, the flexibility shifts towards the heating sector and electrical batteries.
The Highland Plateau region, in San Luis Potosí, involves particular dynamics and needs from those presented within the rest of the state; its culture, vocation, mineral resources and territory, converge to give rise to a unique and particular region. The connectivity within the region has been decisive for its development, since two of the largest and most important national roads in go through this territory.
Despite comprehending about a half of the state's territory, this region has not managed to truly influence the state statistics neither economically nor socially; on the contrary, the employment rate has significantly decreased significantly, and also its population number.
Accordingly, this research aims to analyze the connectivity system within this region to strengthen and complement the development tools of these communities in a sustainable manner and, in this way, increase the welfare of the Highland Plateau population.
Throughout this investigation, it will be possible to understand how the location of this physical network, as well as for the use of resources for the satisfaction of the inhabitants, has been reflected in the communities within this region. Likewise, the statements made by state directors in charge of the economy, road network and social development within the region, will be studied. These statements will also be combined with a “functional grid analysis”, the connectivity between communities and their basic needs.
This year’s research topic concerns the allocation mechanism in the reinsurance market and the potential disadvantages it can entail. The project can thus be classified in the discipline of ‘market design’, which builds upon microeconomics and game theory. As the project progresses, first the theoretical framework will be established and placed in the reinsurance context. The second part will offer insight into and an outlook upon current research questions.
The Production of Isophorone
(2023)
Isophorone is a technically important compound used as a high-boiling-point solvent for coatings, adhesives, etc., and it is used as a starting material for various valuable compounds, including isophorone diisocyanate, a precursor for polyurethanes. For over 80 years, isophorone has been synthesized via base-catalyzed self-condensation of acetone. This reaction has a complex reaction mechanism with numerous possible reaction steps including the formation of isophorone, triacetone dialcohol, and ketonic resins. This review provides an overview of the different production processes of isophorone in liquid- and vapor-phase and reviews the literature-reported selectivity toward isophorone achieved using different reaction parameters and catalysts.
Habitat loss due to land use and land cover change (LUCC) has been identified as the main cause of global environmental change, responsible for biodiversity decline and the deterioration of ecological processes. Habitat loss and fragmentation have been driven by
processes of LUCC such as deforestation, agricultural expansion and intensification, urbanization, and globalization. The objective of this research was to determine the effects of LUCC on the process of habitat loss and the patterns of fragmentation in the surrounding landscape of the Pacuare Reserve (PR) in the Caribbean lowlands of Costa Rica. The PR is a protected area of 800 ha surrounded by an agricultural landscape with a history of over 150 years of bananas monocultures. Landsat satellite images from 1978 to 2020 were used to conduct a temporal analysis of LUCC around the PR. Patterns of change were explored using landscape metrics from the land classification images. To explore potential connectivity routes, the least cost path analysis was used to connect the PR to other protected areas. Overall, forest cover decreased in the study area at a rate of -4.8% per year during the period of 1992-1997. In the year 2001 it reached its lowest cover and then increased at a mean annual rate of 1.6%. A mean overall accuracy of 92% was obtained for the land classification process. A clear fragmentation process was observed, as shown by a decreased in forest mean patch area and largest patch index and by the increase in patch density. Although forest cover increased in the last decade, fragmentation metrics suggest this recover happened in a spatially scattered manner, due to agricultural land abandonment. Connectivity maps showed the importance of forest fragments and of the already established biological corridors for the movement of species to and from the PR, however it also evidenced the lack of connectivity between the coastal forest fragments and further inside the country located protected areas, as well as the need to promote reforestation projects, particularly between fragments of the corridors identified.
In this work, supported cellulose acetate (CA) mixed matrix membranes (MMMs) were prepared and studied concerning their gas separation behaviors. The dispersion of carbon nanotube fillers were studied as a factor of polymer and filler concentrations using the mixing methods of the rotor–stator system (RS) and the three-roll-mill system (TRM). Compared to the dispersion quality achieved by RS, samples prepared using the TRM seem to have slightly bigger, but fewer and more homogenously distributed, agglomerates. The green γ-butyrolactone (GBL) was chosen as a polyimide (PI) polymer-solvent, whereas diacetone alcohol (DAA) was used for preparing the CA solutions. The coating of the thin CA separation layer was applied using a spin coater. For coating on the PP carriers, a short parameter study was conducted regarding the plasma treatment to affect the wettability, the coating speed, and the volume of dispersion that was applied to the carrier. As predicted by the parameter study, the amount of dispersion that remained on the carriers decreased with an increasing rotational speed during the spin coating process. The dry separation layer thickness was varied between about 1.4 and 4.7 μm. Electrically conductive additives in a non-conductive matrix showed a steeply increasing electrical conductivity after passing the so-called percolation threshold. This was used to evaluate the agglomeration behavior in suspension and in the applied layer. Gas permeation tests were performed using a constant volume apparatus at feed pressures of 5, 10, and 15 bar. The highest calculated CO2/N2 selectivity (ideal), 21, was achieved for the CA membrane and corresponded to a CO2 permeability of 49.6 Barrer.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores walnuts export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores vanilla export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic/fair trade coffee export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic tofu export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic rye export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Agnieszka Gehringer of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic oranges export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic oats export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic lipstick export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of Cologne University of Applied Sciences and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic cotton export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic coconut oil export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic chickpeas export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic canned tomatoes export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic canned corn export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores organic black tea export opportunities to the German and US markets.
This market research paper has been prepared under the supervision of Prof. Dr. Wolfgang Veit of TH Köln and Prof. Dr. Carol Scovotti of University of Wisconsin-Whitewater in the course of the inter-university cross-border collaboration student research project “Export Opportunity Surveys (EOS)”. This study explores fresh organic strawberries export opportunities to the German and US markets.
The prolonged US-China trade tension, initiated in 2017, has led to significant consequences, impacting global supply chains and causing economic tension between the two largest economies. Particularly affecting the automotive sector, the trade war has influenced motor insurance premiums in China, contributing to a declining trend in non-life insurance growth rates from 2017 to 2021. However, a positive outlook is projected for 2023-2026, indicating potential recovery opportunities. The trade war's short-term impacts on the Chinese motor insurance market include increased costs, low premium growth, and economic challenges. In the long term, transformative changes, including market diversification, innovative products, data-driven pricing, and technology-enabled risk prevention, are expected to shape a dynamic and competitive motor insurance landscape in China, offering growth potential despite initial challenges.
In Sierra Leone, at the moment 10 out of the total 14 districts are faced with the problem of large-scale land investments for industrial agriculture (oil palm, sugarcane…). The production is mainly for the local, regional and world market. There are quite many of these investments in the planning stage, while some are extending their operations by taking more land from communities or are already at the production stage. Studies and media reports have claimed a number of negative impacts felt in communities hosting these companies, ranging from loss of land, food insecurity, increase in poverty to loss of livelihoods, environmental degradation as well as social and cultural problems. The goal of this thesis is to examine the impacts of the operations of “Socfin Agriculture Company” on food security of local communities in Malen Chiefdom, Pujehun District of Sierra Leone.
Both quantitative and qualitative research methods are used for data collection, analyses, and interpretation of results. The research uses household income and expenditure to compare household food security before and after the start of the company’s operations. It examines consequences of community’s loss of land to support household food production versus casual wage earn from employment created by the company to meet household food security.
The results show a loss of household’s income sources and a significant decrease in households’ income. Households’ food crop production has reduced accompanied by a complete loss of cash crop farming. Households affected by the operations of the company have lost access to land and other natural resources that support food production. Furthermore, the company employs very few people in comparison to the total population of affected communities. Calculation of total wage earn from employment by the company cannot meet the staple food (rice) needs of the households. Also, households claimed a host of unfilled promises made by the company and national government at the onset of the operations of the company.
In conclusion, household food production is the most significant determinant for household food security, with regards to food availability, accessibility, utilization and stability of supply. Therefore, national government should carefully study and develop a framework that addresses food security of households impacted by the operations of the rapidly growing large-scale land investment companies and ensure a fair share of the local community in the economic development of the country and suggesting ways of improving access rights in the context of tenure.
The geography of European cross-border banking : the impact of cultural and political factors
(2009)
We investigate the determinants of European banking market integration with a focus on the potentially limiting role of cultural and political factors. Employing a unique data set of European cross-border loans and deposits, the study uses various gravity models that are augmented by societal proxies. While trade-theoretic reasoning can explain part of the surge in cross-border banking, we demonstrate that distance and borders still matter in the geography of European cross-border banking. Moreover, we can identify cultural differences and different legal family origin as important barriers to integration.
The whole site of the waste disposal centre Leppe in Lindlar has been modified by the project :metabolon into an authentic learning site for knowledge transfer. Addressing all age groups, the project offers insights into environmental knowledge and explains contexts of resources and material flows. The site conditions allow practical outlooks on future energy systems. Following the meta theme of “lifetime learning”, pupils and students are addressed by different modules, considering their individual learning levels.
In water electrolyzers, polymer electrolyte membranes (PEMs) such as Nafion can accumulate cations stemming from salt impurities in the water supply, which leads to severe cell voltage increases. This combined experimental and computational study discusses the influence of sodium ion poisoning on the ionic conductivity of Nafion membranes and the ion transport in a thereon based water electrolysis cell. Conductivities of Nafion and aqueous solutions with the same amount of dissolved cations are measured with impedance spectroscopy and compared with respect to Nafion’s microstructure. The dynamic behavior of the voltage of a water electrolysis cell is characterized as a function of the sodium ion content and current density, showing the differences of the ion transport at alternating and direct currents. These experimental results are elucidated with a physical ion transport model for sodium ion poisoned Nafion membranes, which describes a proton depletion and sodium ion accumulation at the cathode. During proton depletion, the cathodic hydrogen evolution is maintained by the water reduction that forms hydroxide ions. Together with sodium ions from the membrane, the formed hydroxide ions can diffuse pairwise into the water supply, so that the membrane’s sodium ions can be at least partly be replaced with anodically formed protons.
While global food production greatly exceeds dietary energy demand, undernutrition remains, and diets largely fail to ensure the health of the population. Agricultural biodiversity is crucial for the world’s food security, but genetic diversity has been degraded. In Mexico, the dietary transition towards processed foods has contributed to malnutrition and a rise of diet-related chronic diseases. Mexico’s indigenous people are conserving and creating valuable plant genetic resources in their swidden milpas and traditional agroforestry systems but remain the country’s most vulnerable population group. The Teenek (or Huastec), an indigenous group that habitat the Huasteca Potosina, a region in north-eastern Mexico cultivate a high diversity of edible plants in their home gardens (solar), milpas, and agroforestry systems (te’lom, or finca). However, migration has been leading to the abandonment of traditional farming in the region.
The objective of this study was to analyse if the managed agricultural biodiversity of the different traditional land use systems contributes to the food security of the farming households in the community of Jol Mom. Food availability and access were investigated. In total, 40 households were surveyed. Dietary patterns were identified through principal component analysis. Informal interviews, semi-structured interviews and participant observation allowed to account for the people’s own perceptions and provided additional insights. Findings showed that traditional Teenek farming systems are the source of a variety of nutritious foods and resulted to be the most important provider of fruits and vegetables. The average production diversity was 34 out of 56 crops, farmers cultivating more than one or two farming systems showed an increase of four and 11 produced species respectively. Production diversity was strongly correlated with food variety in a household’s diet, with an increment of one per 0.85 produced crop. Two main diverging dietary patterns were revealed, a westernized diet relying largely on purchased foods, to which the younger generation was more inclined, and a traditional diet characterized by a high consumption of cultivated products, mostly observed in the older households.
In conclusion, farming households in Jol Mom profit from the agricultural diversity of their production systems, either through the consumption of nutritious foods or by the sale of agricultural products. However, a tendency towards nutrient-poor diets was observed. Increasing agricultural diversity and consumption of locally produced foods might help to fight this trend but would require a valorisation of traditional foods and an appreciation of the contribution of indigenous people’s traditional agriculture to food security.
State of the art browser games are increasingly complex pieces of software with extensive code basis. With increasing complexity, a software becomes harder to maintain. Automated regression testing can simplify these maintenance processes and thereby enable developers as well as testers to spend their workforce more efficiently.
This thesis addresses the utilization of automated tests in web applications. As a use case test automation is applied to an online-based strategy game for the browser. The introduction presents the general conditions for a software project that makes use of automated tests and different approaches of test automation. The main section introduces a specific solution of test automation applied on the game “Forge of Empires”, produced by Innogames GmbH. The created framework of the company is presented. It implements different software frameworks. The conclusion consists of a comparison and analysis about the presented methods and technologies.
This study explores the potential of robust, strongly basic type I ion exchange resins—specifically, Amberlyst® A26 OH and Lewatit® K 6465—as catalysts for the aldol condensation of citral and acetone, yielding pseudoionone. Emphasis is placed on their long-term stability and commendable performance in continuous operational settings. The aldol reaction, which traditionally is carried out using aqueous sodium hydroxide as the catalyst, holds the potential for enhanced sustainability and reduced waste production through the use of basic ion exchange resins in heterogeneous catalysis. Density Functional Theory (DFT) calculations are employed to investigate catalyst deactivation mechanisms. The result of these calculations indicates that the active sites of Amberlyst® A26 OH are cleaved more easily than the active sites of Lewatit® K 6465. However, the experimental data show a gradual decline in catalytic activity for both resins. Batch experiments reveal Amberlyst® A26 OH’s active sites diminishing, while Lewatit® K 6465 maintains relative consistency. This points to distinct deactivation processes for each catalyst. The constant count of basic sites in Lewatit® K 6465 during the reaction suggests additional factors due to its unique polymer structure. This intriguing observation also highlights an exceptional temperature stability for Lewatit® K 6465 compared to Amberlyst® A26 OH, effectively surmounting one of the prominent challenges associated with the utilization of ion exchange resins in catalytic applications.
Digital competences are describing a set of skills, which are necessary to use digital devices and tools with an adequate degree of self-determination. With the ubiquitous digitization of our lives and our society it is important for every citizen to have digital competences. Therefor, it is necessary to educate those competences in schools. As one cannot assume teachers to have enough digital competences to well educate the children of todays classes, this master thesis tries to find out: How to shape the process of teaching digital competences to adolescents in German schools, focusing on including multiple parties from diverse backgrounds into the process? At first, the current situation of teaching digital competences in German schools is analyzed by means of a literature review. After the identification of the challenges within the German system, international best practices are examined. Therefor, four countries, which have reached high scores in the International Computer and Information Literacy Study are selected. Australia, the Czech Republic, Denmark and the Republic of Korea are compared and possible chances for Germany identified. As the next step, expert interviews with divers parties, which have direct or indirect relation to the German education system, are held. The goal of the interviews is to generate ideas on how to support the education system by external help. At the end of the thesis the recommended approach of Motivating External People is presented. Several measures, such as teaching or mentoring students in a guest lecturer model; providing IT support for the hard- and software of the schools or creating Open Educational Resources as education material for the teachers are presented and possible third parties are named. As it is not possible to support the education system from the outside without education system internal persons, it is presented, what needs to change within the system to get the approach working. Therefor, not a complex and system changing approach is presented, but a combined top-down and bottom-up process to motivate external people to support.
The teaching of civil engineering consists of different didactic approaches, such as lectures, group work or research-based teaching, depending on the respective courses. Currently, the metaverse is gaining importance in teaching and offers the possibility of a new teaching approach for civil engineering and especially for the teaching of courses from the areas of “Digital Design and Construction”. Although the advantages of teaching in the metaverse, such as location and time independence or a higher learning outcome, are mentioned in the literature, there are also challenges that must be considered when teaching in the metaverse. Against this background, this paper examines the implications of using the metaverse as a teaching tool in teaching “Digital Design and Construction”. The impact of teaching BIM in the metaverse is evaluated by (1) a literature review and workshops to evaluate use cases and demands for extended reality (XR) and the metaverse, (2) integrating XR and the metaverse in the courses and valuation by quantitative evaluations and (3) analyzing student papers of the courses and outcomes of a World Café. Due to these steps, this paper presents a novel approach by reflecting the students’ perspective. Furthermore, this paper presents a validated approach for integrating BIM and the metaverse in teaching.
Table Tennis Tutor: Forehand Strokes Classification Based on Multimodal Data and Neural Networks
(2021)
Beginner table-tennis players require constant real-time feedback while learning the fundamental techniques. However, due to various constraints such as the mentor’s inability to be around all the time, expensive sensors and equipment for sports training, beginners are unable to get the immediate real-time feedback they need during training. Sensors have been widely used to train beginners and novices for various skills development, including psychomotor skills. Sensors enable the collection of multimodal data which can be utilised with machine learning to classify training mistakes, give feedback, and further improve the learning outcomes. In this paper, we introduce the Table Tennis Tutor (T3), a multi-sensor system consisting of a smartphone device with its built-in sensors for collecting motion data and a Microsoft Kinect for tracking body position. We focused on the forehand stroke mistake detection. We collected a dataset recording an experienced table tennis player performing 260 short forehand strokes (correct) and mimicking 250 long forehand strokes (mistake). We analysed and annotated the multimodal data for training a recurrent neural network that classifies correct and incorrect strokes. To investigate the accuracy level of the aforementioned sensors, three combinations were validated in this study: smartphone sensors only, the Kinect only, and both devices combined. The results of the study show that smartphone sensors alone perform sub-par than the Kinect, but similar with better precision together with the Kinect. To further strengthen T3’s potential for training, an expert interview session was held virtually with a table tennis coach to investigate the coach’s perception of having a real-time feedback system to assist beginners during training sessions. The outcome of the interview shows positive expectations and provided more inputs that can be beneficial for the future implementations of the T3.
Urban settlements demand the highest levels of resource consumption and waste management.
It has been accepted that cities should be considered organisms. Through Urban Energy Metabolism the planning and management of energy that flows across cities achieves important developments towards sustainability. Energy Efficiency is one of the primary tools used to produce sustainable development. Cities worldwide are developing action plans that implement the teachings of holism and eco-friendly practices. Systems Theory is a field developed with the intention of managing systems based on interdisciplinarity and a holistic approach. Fundamental practices of systems thinking are applicable to the study of cities as sustainable organisms/complex systems. Planning for Energy Efficient Cities (PLEEC) is an European project that was executed by a group of participants from the public, private, and education sectors, with the purpose of designing energy efficiency action plans to meet the targets of 2020. This work introduces, based on a literature review, several systems theories. A critique of the characteristics of PLEEC’s framework is performed to assess the level of systemic consideration into holism and sustainability. The evaluation of the process or success of the energy efficiency plans elaborated is not in the scope of the research. Using a modified version of Michael C.
Jackson’s Total Systems Intervention and a table that summarizes the principles of systems thinking, it is concluded that the plan lacks systemic consideration of cities as complex systems. The framework includes several concepts attributed to the field, such as interconnection of elements exchanging information and resources, but fails in defining self-organizing feedback based structures and function-driven behavior. It is of paramount importance that system thinking basics be at the core of all planning.
Emergency management services, such as firefighting, rescue teams and ambulances,are all heavily reliant on road networks. However, even for highly industrialised countries such asGermany, and even for large cities, spatial planning tools are lacking for road network interruptionsof emergency services. Moreover, dependencies of emergency management expand not only onroads but on many other systemic interrelations, such as blockages of bridges. The first challenge thispaper addresses is the development of a novel assessment that captures systemic interrelations ofcritical services and their dependencies explicitly designed to the needs of the emergency services.This aligns with a second challenge: capturing system nodes and areas around road networksand their geographical interrelation. System nodes, road links and city areas are integrated into aspatial grid of tessellated hexagons (also referred to as tiles) with geographical information systems.The hexagonal grid is designed to provide a simple map visualisation for emergency planners andfire brigades. Travel time planning is then optimised for accessing city areas in need by weighingimpaired areas of past events based on operational incidents. The model is developed and testedwith official incident data for the city of Cologne, Germany, and will help emergency managers tobetter device planning of resources based on this novel identification method of critical areas.
Due to the worldwide shortage of petrochemical based resources, the usage of renewable bio-based raw materials for established and novel products becomes increasingly important.[1] Such bio-based resources are already used for the fabrication of a variety of products, e. g. paper, lubricants, detergents or cosmetics. In the future they are expected to emerge in many more applications in industry and household.[1]
A very promising approach relies on the use of glycolipids as a source of hydroxy-oleic acid.[2] Microbial glycolipids are produced for instance via fermentation from natural resources such as plant oils and sugar.[3] After fermentation complex product mixtures are obtained with the composition depending on the microorganism, substrate and fermentation time.[3] The successful use of microbial glycolipids and hydroxy-oleic acid (HOA) derived therefrom as bio-based intermediates requires reliable analytical methods as well as robust manufacturing processes for the synthesis and cleavage of bio-based molecules. In order to obtain hydroxy-oleic acids as bio-based intermediates, the acidic cleavage of microbial derived sophorolipid was investigated. In addition the implementation of HOA in polyurethane (PU) systems was explored.
Linoleic acid hydroperoxides are versatile intermediates for the production of green note aroma compounds and bifunctional ω-oxo-acids. An enzyme cascade consisting of lipoxygenase, lipase and catalase was developed for one-pot synthesis of 13-hydroperoxyoctadecadienoic acid starting from safflower oil. Reaction conditions were optimized for hydroperoxidation using lipoxygenase 1 from Glycine max (LOX-1) in a solvent-free system. The addition of green surfactant Triton CG-110 improved the reaction more than two-fold and yields of >50% were obtained at linoleic acid concentrations up to 100 mM. To combine hydroperoxidation and oil hydrolysis, 12 lipases were screened for safflower oil hydrolysis under the reaction conditions optimized for LOX-1. Lipases from Candida rugosa and Pseudomonas fluorescens were able to hydrolyze safflower oil to >75% within 5 h at a pH of 8.0. In contrast to C. rugosa lipase, the enzyme from P. fluorescens did not exhibit a lag phase. Combination of P. fluorescens lipase and LOX-1 worked well upon LOX-1 dosage and a synergistic effect was observed leading to >80% of hydroperoxides. Catalase from Micrococcus lysodeikticus was used for in-situ oxygen production with continuous H2O2 dosage in the LOX-1/lipase reaction system. Foam generation was significantly reduced in the 3-enzyme cascade in comparison to the aerated reaction system. Safflower oil concentration was increased up to 300 mM linoleic acid equivalent and 13-hydroperoxides could be produced in a yield of 70 g/L and a regioselectivity of 90% within 7 h.
Abstract
(−)‐Menthol is one of the most popular aroma compounds worldwide. While in the past mostly extracted from mint plants, today (−)‐menthol synthesis from other raw materials is becoming more relevant. Common starting materials for menthol synthesis are m‐cresol, citral and myrcene, but also substrates like menthone, mono‐ and bicyclic terpenes and terpenoids have been used for this purpose in the past. As for many applications (−)‐menthol of high purity is required, asymmetric syntheses and enantiomeric resolution of obtained raw products are applied for menthol production. This review gives an overview on the most important synthetic menthol production processes of the companies Symrise, Takasago and BASF and relevant literature in the field of menthol synthesis with a focus on the last 20 years.
This article explores the relationship between digital transformation and disaster risk.Vulnerability studies aim at differentiating impacts and losses by using fine-grained information fromdemographic, social, and personal characteristics of humans. With ongoing digital development,these characteristics will transform and result in new traits, which need to be identified andintegrated. Digital transformations will produce new social groups, partly human, semi-human,or non-human—some of which already exist, and some which can be foreseen by extrapolating fromrecent developments in the field of brain wearables, robotics, and software engineering. Thoughinvolved in the process of digital transformation, many researchers and practitioners in the field ofDisaster Risk Reduction or Climate Change Adaptation are not yet aware of the repercussions fordisaster and vulnerability assessments. Emerging vulnerabilities are due to a growing dependency ondigital services and tools in the case of a severe emergency or crisis. This article depicts the differentimplications for future theoretical frameworks when identifying novel semi-human groups and theirvulnerabilities to disaster risks. Findings include assumed changes within common indicators of socialvulnerability, new indicators, a typology of humans, and human interrelations with digital extensionsand two different perspectives on these groups and their dependencies with critical infrastructure.
Elaeis guineensis Jacq. or oil palm is a native species of West Africa. Its oils, extracted from the fruit mesocarp and the kernel are widely used in the food industry, industrial applications, and bioenergy production. Due to its versatility, profitability and growing demand, the global oil palm agroindustry raises concerns regarding deforestation, effects in biodiversity, contamination and related to social issues such as labor conditions, poverty, and social conflicts. In Mexico, the establishment and subsequent growth of the oil palm industry was promoted by past government policies and financial support. In Chiapas the current main producer of the country, the expansion can be also attributed to oil palm resilience to floods, hurricanes, and the economic profitability.
The objective of this study is to evaluate the sustainability status of the oil palm production system within Acapetahua and Villa Comaltitlán Municipalities by analyzing the indicators of sustainability. To achieve this, the Evaluation Framework for Natural Resource Management Systems (MESMIS), was adapted to measure the attributes status of productivity, stability, reliability, resilience, self-management, equity, and adaptability, of the different dimensions of sustainability (environmental, social, political, and economic).
It was identified that MESMIS is an appropriate framework to study oil palm system in Acapetahua and Villa Comaltitlán municipalities. The methodology allowed the identification of critical points, and relevant indicators that include land use and vegetation cover changes, oil palm cashflow, good agricultural practices, farmers´ training, level of participation and farmers´ well-being. As a result, it was identified that vegetation and land use changes were principally from pastures land and previous oil palm plantations, and a positive profitability in the last two years. Soil and water conservation practices are implemented, and farmers have received different trainings principally from social mills, but other good agricultural practices and awareness of social problems should be improved, while the social participation evaluation showed a weak status of the political dimension.
The majority of Niger ’s population faces a widespread lack of access to electricity. Althoughthe country lies in the Sahara belt, exploitation of solar energy is so far minimal. Due to ongoing fossilfuel exploration in the country, this fuel might dominate the future electricity supply. Today, Nigerimports the most of its electricity from Nigeria. There is a need to expand electricity generation andsupply infrastructures in Niger. When doing so, it is important to choose a proper set of electricitygeneration resource/technology that fulfils sustainability criteria. Thus, the objective of this work isto analyze a methodology in order to assess different energy technologies for Niger. A multi-criteriadecision approach was selected to assess the most accessible energy system for the country. Forthis purpose, indicators were developed and weighted for ranking electricity generation options.Altogether 40 indicators are selected under six dimensions (availability, risk, technology, economics,environment and social) to assess eight different alternatives, considering the aggregated results andcorresponding scores under each dimension. A merit list of technology and resources for electricitygeneration presented in this work could support the stakeholders in their decision-making for furtherprojects implementation in the country.
Porous polymer membranes substantially contribute to an acceleration of sustainability transformation based on the energy efficient separation of liquid and gaseous mixtures. This rapid shift toward sustainable industrial processes leads to an increased demand for specifically tailored membranes. In order to predict membrane performance factors like permeability, selectivity and durability, the membrane formation process by film casting and phase inversion needs to be understood further. In recent years, computational models of the membrane formation process have been studied intensely. Their high spatial and temporal resolution allows a detailed quantitative description of phase inversion phenomena. New experimental techniques complement this development, as they provide quantitative data, e.g., on compositional changes of the polymer solution during membrane formation as well as the kinetic progression of the phase separation process. This state-of-the-art review compiles computational and experimental approaches that characterize the phase inversion process. We discuss how this methodological pluralism is necessary for improving the tailoring of membrane parameters, but that it is unlikely to be the way to the ultimate goal of a complete description of the evolution of the membrane structure from the initial demixing to the final solidification. Alternatively, we formulate an approach that includes a database of standardized and harmonized membrane performance data based on previously publicized data, as well as the application of artificial neural networks as a new powerful tool to link membrane production parameters to membrane performance.
Due to reasons of sustainability and conservation of resources, polyurethane (PU)-based systems with preferably neutral carbon footprints are in increased focus of research and development. The proper design and development of bio-based polyols are of particular interest since such polyols may have special property profiles that allow the novel products to enter new applications. Sophorolipids (SL) represent a bio-based toolbox for polyol building blocks to yield diverse chemical products. For a reasonable evaluation of the potential for PU chemistry, however, further investigations in terms of synthesis, derivatization, reproducibility, and reactivity towards isocyanates are required. It was demonstrated that SL can act as crosslinker or as plasticizer in PU systems depending on employed stoichiometry. (ω-1)-hydroxyl fatty acids can be derived from SL and converted successively to polyester polyols and PU. Additionally, (ω-1)-hydroxyl fatty acid azides can be prepared indirectly from SL and converted to A/B type PU by Curtius rearrangement.
The oxidation of cumene and following cleavage of cumene hydroperoxide (CHP) with sulfuric acid (Hock rearrangement) is still, by far, the dominant synthetic route to produce phenol. In 2020, the global phenol market reached a value of 23.3 billion US$ with a projected compound annual growth rate of 3.4% for 2020–2025. From ecological and economical viewpoints, the key step of this process is the cleavage of CHP. One sought-after way to likewise reduce energy consumption and waste production of the process is to substitute sulfuric acid with heterogeneous catalysts. Different types of zeolites, silicon-based clays, heteropoly acids, and ion exchange resins have been investigated and tested in various studies. For every type of these solid acid catalysts, several materials were found that show high yield and selectivity to phenol. In this mini-review, first a brief introduction and overview on the Hock process is given. Next, the mechanism, kinetics, and safety aspects are summarized and discussed. Following, the different types of heterogeneous catalysts and their performance as catalyst in the Hock process are illustrated. Finally, the different approaches to substitute sulfuric acid in the synthetic route to produce phenol are briefly concluded and a short outlook is given.
Worldwide there is a big need for affordable livingspace. Globalization leads to a connection of development and ideas in the field of building. Open Source communities could improve and accelerate this development. The potential of theses communities lies in the connection of different diciplines. Especially for building projects with a small budget and a willingness to participate in the work process open source do-it-yourself constructions are a great opportunity to help cover the need of affordable work and living space. Renewable materials such as wood offer great potential here. New, standardised technologies make a decentralised production possible.
The ‘cyber’ threat is regarded as a growth area in the
primary and reinsurance sectors worldwide and for the past five years has been developing more dynamically than any other hazard. This major topic concerns both primary and reinsurance companies in all areas, whether in property, liability, transport or accident insurance. Services (prevention, risk-based pricing models and claims processing, for example) present a global growth market for the reinsurance industry. The complexity of the cyber threat and the evolving nature of the risk involved present a host of challenges for the design of insurance products, for underwriting, for risk management and for cumulative control – for both primary and reinsurance companies. Correct assessment of cyber risk is therefore indispensable, and the right approach must always be developed further. Special attention needs to be given to the variety of forms a cyber event can take. Thus, primary and reinsurance companies can incur not only the costs of data loss, but also the costs of
reconstructing IT infrastructure, the costs of network and business interruptions, costs of crisis management, costs of reputational risk, and the costs of third-party liability claims.
Ten years after the journal’s first publication, we are taking a closer look at the knowledge flows of the output of the journal Publications. We analyzed the papers, topics, their authors and countries to assess the development of scholarly communication within Publications. Our bibliometric analyses show the research journal’s community, where the knowledge of this community is coming from, where it is going, and how diverse the community is based on its internationality and multidisciplinarity. We compare these findings with the scopes and topical goals the journal specifies. We aim at informing the editors and editorial board about the journal’s development to advance the journal’s role in scholarly communication. The results show that regarding topical diversity and internationality, the journal has remarkably developed. Moreover, the journal tends towards the field of library and information science, but strengthens its multidisciplinary status via its topics and author backgrounds.
Based on the idea of sustainable development, the BioTrade principles and criteria (P&C), based on the idea of sustainable development, have been the essential core guiding the implementation of BioTrade activities since their inception by UNCTAD in 2007. However, after identifying that BioTrade of medicinal plants causes negative impacts on the traditional knowledge related to these plants, the P&C were evaluated in light of the most relevant international agreements that contribute to the safeguarding of this knowledge. The result obtained from the assessment showed that the P&C present many gaps that prevent evaluating the real impact of trade on the traditional knowledge of medicinal plants in Indigenous and local communities. Therefore, in the same framework of the current P&C, the main recommendations contained in the international agreements and the suggestions of specialists in the field have been gathered to create a BioTrade standard that contributes to safeguarding traditional medicinal plant knowledge within a commercial context in any BioTrade initiative where the commercialized product is a sacred or native plant with traditional and cultural value for a community.
New risk geographies are emerging with war and conflict resurfacing, including nuclear threats. This poses challenges to civil protection for conducting risk-informed preparedness planning. A spatial assessment of Germany and Europe is conducted using a geographic information system. Buffer circles of nuclear explosion effects and fallout buffers show potentially exposed areas around major cities. Different scenarios indicate shrinking areas safe from exposure. However, even in a densely populated country, rural areas and smaller cities can be identified that could provide sites for evacuation shelters. Changing wind directions poses a challenge for civil protection planning because fallout risk covers most German territory even when few cities are attacked. However, wind speeds and topography can help identify suitable shelter areas. More knowledge about the temporal development of a nuclear explosion and its specific forms of harm can also help to improve risk knowledge and planning. While nuclear warfare at first seems to render useless any option for safe areas and survival, the spatial risk assessment shows that exposure does not occur at all places at all times. Being safe from harm will be difficult in such a worst-case scenario, but avoiding large city perimeters and being informed can also help reduce risk.
Remote rural populations do not often have the luxury of viable multisource electricity generation systems. Considering fossil fuels for remote populated areas is not often a viable option due to the fuel transportation costs and the population’s socioeconomic status. Extending the grid is often economically prohibitive. This paper proposes possible ways in which Mali could increase the rate of population with access to electricity by 2050 using Low Emission Analysis Platform (LEAP) and geographical information tools. The current energy situation is assessed, and multiple demand and supply scenarios are created to find the most viable option in environmental and economic dimensions. A minimum of 50% reduction of biomass consumption in the residential sector and a maximum of 71% was achieved through the combination of grid extension and decentralized solar PV. Solar PV becomes the preferable option when enough time for the effects of electricity on income is given. When these effects are not present, solar PV is still a better option, as the amount of biomass replaced with electricity is reduced.
Web browsers use HTTP caches to reduce the amount of data to be transferred over the network and allow Web pages to load faster. Content such as scripts, images, and style sheets, which are static most of the time or shared across multiple websites, are stored and loaded locally when recurring requests ask for cached resources. This behaviour can be exploited if the cache is based on a naive implementation. This paper summarises possible attacks on the browser cache and shows through extensive experiments that even modern web browsers still do not provide enough safeguards to protect their users. Moreover, the available built-in as well as addable cache controls offer rather limited functionality in terms of protection and ease of use. Due to the volatile and inhomogeneous APIs for controlling the cache in modern browsers, the development of enhanced user-centric cache controls remains -until further notice- in the hands of browser manufacturers.
Food insecurity, poor nutrition and poverty are closely linked and entail adverse consequences for the health and well-being of children and adults. They constitute major constraints to development efforts as they can imply lifelong negative effects on human development with impairments on physical and mental capacities of a population, resulting in an overall lower productivity and economic growth potential.
Urban agriculture has been advocated as a strategy to improve food security. This paper exemplifies an urban gardening project that addresses food security and economic resilience of the Syrian refugees and vulnerable Lebanese host communities executed in the suburbs of Beirut. The hypothesis underpinning this study is that urban agriculture holds the potential to contribute to increased food security and reduced urban poverty, by increasing the availability and accessibility to a variety of fresh foods that are rich in vital nutrients and by functioning as a source of livelihoods and income.
The brutality of the Syrian Civil War, it’s massive damage and destruction of housing and persecutions for ethnic cleansing led more than a quarter of its originally 24 million inhabitants to seek safety in neighboring countries and Europe. The war has severely hampered the stability and development throughout the region as hundreds of thousands of refugees have fled to neighboring countries where they often compete with host communities over housing, labor, water, food and land. In relative numbers the biggest burden fell on the riparian country Lebanon, currently holding the highest ratio of refugees to nationals in the world. The small Arab country has already been suffering from many pre-existing challenges as food insecurity and widespread poverty.
The high dependence on food assistance, limited access to income and uncertainties on the amount of food aid provided in each upcoming year, all contribute to an unstable and low food security status of Syrian refugee households in Lebanon with spill overs to vulnerable host communities. In 2017, 91% of Syrian families residing in Lebanon remained food insecure to some degree and the share of household’s falling into severe food insecurity keeps increasing with every year.
These numbers provide clear evidence that current efforts of providing food assistance are not sufficient to combat the repercussions of the crisis and get the situation under control.
The paper displays the impact of the urban gardening project on the food security and economic resilience of participating household’s, as well as lessons learned on the project design during and after the implementation phase. The sampling frame is comprised of Syrian and Lebanese families participating in the project. Primary data were derived from a survey using a questionnaire with a sample size of 41 households. The findings aim to enable stakeholders to improve the performance of similar projects in the future and support relevant government authorities, international aid institutions, non-profits and the civic society towards creating sustainable long-term solutions to increase the self-reliance of refugees by providing insights of the suitability of UA for multiple objectives and by highlighting potential challenges and risks.
Pressure injuries remain a serious health complication for patients and nursing staff. Evidence from the past decade has not been analysed through narrative synthesis yet. PubMed, Embase, CINAHL Complete, Web of Science, Cochrane Library, and other reviews/sources were screened. Risk of bias was evaluated using a slightly modified QUIPS tool. Risk factor domains were used to assign (non)statistically independent risk factors. Hence, 67 studies with 679,660 patients were included. In low to moderate risk of bias studies, non-blanchable erythema reliably predicted pressure injury stage 2. Factors influencing mechanical boundary conditions, e.g., higher interface pressure or BMI < 18.5, as well as factors affecting interindividual susceptibility (male sex, older age, anemia, hypoalbuminemia, diabetes, hypotension, low physical activity, existing pressure injuries) and treatment-related aspects, such as length of stay in intensive care units, were identified as possible risk factors for pressure injury development. Health care professionals’ evidence-based knowledge of above-mentioned risk factors is vital to ensure optimal prevention and/or treatment. Openly accessible risk factors, e.g., sex, age, BMI, pre-existing diabetes, and non-blanchable erythema, can serve as yellow flags for pressure injury development. Close communication concerning further risk factors, e.g., anemia, hypoalbuminemia, or low physical activity, may optimize prevention and/or treatment. Further high-quality evidence is warranted.
Metallic tubular micro-components play an important role in a broad range of products,
from industrial microsystem technology, such as medical engineering, electronics and optoelectronics, to sensor technology or microfluidics. The demand for such components is increasing, and forming processes can present a number of advantages for industrial manufacturing. These include, for example, a high productivity, enhanced shaping possibilities, applicability of a wide spectrum of materials and the possibility to produce parts with a high stiffness and strength. However, certain difficulties arise as a result of scaling down conventional tube forming processes to the microscale. These include not only the influence of the known size effects on material and friction behavior, but also constraints in the feasible miniaturization of forming tools. Extensive research work has been conducted over the past few years on micro-tube forming techniques, which deal with the development of novel and optimized processes, to counteract these restrictions. This paper reviews the relevant advances in micro-tube fabrication and shaping. A particular focus is enhancement in forming possibilities, accuracy and obtained component characteristics, presented in the reviewed research work. Furthermore, achievements in severe plastic deformation for micro-tube generation and in micro-tube testing methods are discussed.
Die Kriterien zur Nachhaltigkeit werden unter der Abkürzung ESG zusammengefasst und sind somit nicht nur auf den reinen Klimawandel begrenzt. Grundsätzlich versteht man unter sogenannten ESG-Kriterien per Definition einen Standard nachhaltiger Investments in den Bereichen Environment/ Umwelt, Social/ gesellschaftliches Engagement und Governance/ Unternehmensführung. (vgl. Haberstock et al., 2019)
Sowohl Erst- und Rückversicherungsunternehmen als auch Retrozessionspartner und Investoren beziehen bei ihrer Geschäftsentscheidung zunehmend Nachhaltigkeitsaspekte mit ein. Sie achten unter anderem auf die Nachhaltigkeit der Kapitalanlagen und die entsprechenden Entscheidungen im Underwriting oder bewerten das soziale Engagement eines Vertragspartners. Deshalb kann sich ein überzeugendes Nachhaltigkeitsprofil auch sukzessive zu einem Wettbewerbsvorteil entwickeln.
Das Kerngeschäft der Rückversicherungsbranche wird immer wieder von neuartigen Risiken und globalen Herausforderungen geprägt.
Eine ESG-konforme Geschäftsausrichtung und eine entsprechende Anpassung im Underwriting stellt den Rückversicherungs- und Retrozessionsmarkt vor neue Herausforderungen, da gewisse ESG-Kriterien eine Hürde für fortlaufende Geschäftstätigkeiten im Underwriting darstellen.
Die Umsetzung einer ESG-konformen Geschäftsausrichtung in der Retrozession geht einher mit der Rekalibrierung des Risikoappetits und mit der Aufnahme von einheitlichen zukünftigen ESG-Ratings, die sowohl zu Vorteilen als auch Nachteilen in der Wettbewerbsfähigkeit führen können.
Vergleicht man die ESG-Faktoren zwischen Retrozedenten und Retrozessionären lässt sich feststellen, dass die ESG-Faktoren für Retrozedenten bei der Kapazitätssuche wichtig sind. Hingegen die Faktoren beim Kapazitätsangebot für Retrozessionäre weniger wichtig sind. Diese Erkenntnis wird dadurch begründet, dass sich Retrozedenten bereits im vorgelagerten Underwriting der eingehenden Risiken mit den ESG-Kriterien beschäftigen müssen und dadurch bereits einen besseren Überblick über diese Faktoren haben. Zudem müssen sich die Retrozedenten im Detail mit den möglichen Retrozessionären und deren ESG-Strategie beschäftigen, damit die ESG-konforme Geschäftsausrichtung gewahrt wird.
Eine ESG-konforme Geschäftsausrichtung und die Berücksichtigung der ESG-Risiken führt zwangsläufig zu einer Anpassung der Geschäftsstrategie, der internen Aufsichtsstrukturen, des Risikomanagements und zu einer Änderung des Pricings von Retrozessionsrisiken.
REST became the go to approach when it comes to large scale distributed systems on, or outside the World Wide Web. This paper aims to give a brief overview of what REST is and what its main draws and benefits are. Secondly, I will showcase the implementation of REST using HTTP and why this approach became as popular as it is today. Based on my research I concluded that REST’s advantages in scalability, coupling, performance and its seamless integration with HTTP enabled it to rightfully overtake classic RPC based approaches.
Abstract
Two types (with and without a hydrolysis stabilizer) of polyamide 6.6 (PA6.6) reinforced with 30% w/w glass fibres were examined against the influence of automotive cooling fluids, e.g. ethylene glycol aqueous solutions. The overall goal was to find a methodology to compare the performance of PA6.6 materials against the impacts of the hydrolysis environment. The stabilizer effect on the hydrolytic resistance of the materials was assessed using tensile tests according to ISO 527, and their strain‐at‐break values were evaluated in more detail. The degradation mechanism of both PA types was monitored by infrared spectroscopy and SEM. The material lifetime was described by the Arrhenius equation. The results show that the hydrolysis stabilizer operates effectively at low temperature but exhibits weak performance above 130 °C, which is explained by faster consumption of the stabilizing agent. © 2021 The Authors. Polymer International published by John Wiley & Sons Ltd on behalf of Society of Industrial Chemistry.
Resilience in relation to flood risk management (FRM) is not a new concept, yet parts of the FRM community are still struggling to apply it. The main challenge this study addresses is the question as to whether parts of the FRM community should still adopt, or rather “leap‐frog,” resilience. The main purpose is to evaluate whether resilience is a still on‐going trend or, already subsiding. Research suggests that resilience is an on‐going trend that connects research and policy and has gained international recognition as expressed by international guidelines and bodies promoting its research but also its operationalization. Academic literature in the area of FRM also shows a significant continuing development. Resilience enables to analyze dynamics and transformations of riverine areas, or coastal zones in connection to an integrated social‐environmental system approach with more emphasis and conceptual basis than previous concepts. Resilience is more than a short‐lived notion and it appears that FRM researchers cannot avoid addressing it. Resilience often is a convergence of ideas and mainstreaming of efforts, which in many venues is absolutely necessary and can help, for example, to decrease silo‐thinking. But as academics, we have a mandate to remain skeptical and remain on the look‐out for novel ideas, too.
This article is categorized under:
Engineering Water > Planning Water
In the last decade, the utilization of waste by-product apple pomace has been extensively researched (due to its difficult disposal) and currently finds beneficial usage in various industries; as substrate for microbial growth or recovery of pectin, xyloglucan and polyphenols. In this research apple juice was produced at pilot scale. Furthermore, apple pomace was employed as substrate for the production of pectin, biofuel (pellets) and concentrated apple pomace extract. Extensive mass and heat balances were conducted to evaluate the feasibility of this approach on industrial scale. The produced pellets had very similar characteristics to wood pellets (net calorific value of 20.3 MJ/kg). Dried apple pomace contained 11.9% of pectin. Fed-batch cultivation of baker´s yeast with apple pomace extract demonstrated a potential for partial substitution of molasses in industrial bioprocesses. This concept shows how a zero discharge biorefinery process converts waste from apple juice production into three valuable products enabling connections between different industries.
Different methods have been proposed for in situ root-length density (RLD) measurement. One widely employed is the time-consuming sampling of soil cores or monoliths (MO). The profile wall (PW) method is a less precise, but faster and less laborious alternative. However, depth-differentiated functions to convert PW RLD estimates to MO RLD measurements have not yet been reported. In this study, we perform a regression analysis to relate PW results to MO results and determine whether calibration is possible for distinct crop groups (grasses, brassicas and legumes) consisting of pure and mixed stands, and whether soil depth affects this calibration. The methods were applied over two years to all crop groups and their absolute and cumulative RLD were compared using a linear (LR) and multiple linear (MLR) regression. PW RLD was found to highly underestimate MO RLD in absolute values and in highly rooted areas. However, a close agreement between both methods was found for cumulative root-length (RL) when applying MLR, highlighting the influence of soil depth. The level of agreement between methods varied strongly with depth. Therefore, the application of PW as the main RLD estimation method can provide reliable estimates of cumulative root distribution traits of cover crops.
The brief lecture addresses reinsurance-relevant aspects of ecosystems in the automotive and mobility field. Specifically, the following aspects will be considered:
• Definition and description of the roles within an ecosystem, paying particular
attention to the role of insurance companies;
• Status and potential drivers of evolving automotive and mobility ecosystems;
• Opportunities for the strategic positioning of reinsurance companies.
Reducing the carbon emissions from hotels on non-interconnected islands (NII) is essential in the context of a low carbon future for the Mediterranean region. Maritime tourism is the major source of income for Greece and many other countries in the region, as well as hot-temperate and tropical regions worldwide. Like many NIIs, Rhodes attracts a high influx of tourists every summer, doubling the island’s energy demand and, given the high proportion of fossil fuels in the Rhodian energy supply, increasing carbon emissions. Using the theoretical framework ‘FINE’, this paper presents the optimisation of a medium-sized hotel’s energy system with the aim of reducing both cost and carbon emissions. By introducing a Photovoltaic (PV) net metering system, it was found that the carbon emissions associated with an NII hotel’s energy system could be reduced by 31% at an optimised cost. It is suggested that large-scale deployment of PV or alternative renewable energy sources (RES) in NII hotels could significantly reduce carbon emissions associated with the accommodation sector in Greece and help mitigate climate change.
This paper studies the process of business cycle synchronization in the European Union and the euro area. As our baseline methodology we adopt rolling window correlation coefficients of various economic indicators, observed since 2000. Among the indicators, we distinguish between real economic indicators, like the real GDP growth and unemployment, and nominal indicators, like inflation and government budget. Given the direct implication of this kind of analysis for the common monetary policy of the European Central Bank (ECB), special attention is paid to the pattern of business cycle synchronization in the core and peripheral members of the euro area. Our analysis of quarterly data covering the first two decades of the euro area shows that there was a certain synchronization tendency in the first years of the common currency. However, the European debt crisis halted the economic integration within the European Union and—even more so—within the euro area. Since the ECB can to a large extent intervene only with “one-size-fits-all” monetary policy instruments, this renders increasingly cumbersome the conduct of stabilisation policies within the euro area.
Urbanization processes are one of the main factors for habitat loss and fragmentation, driving global biodiversity loss and species extinction. The neotropical Atlantic forest in Brazil is considered a global key biodiversity hotspot and used to be one of the most extensive forests of the Americas. Due to substantial deforestation over centuries, its landscape was transformed into a mosaic of small forest fragments surrounded by a predominantly agricultural matrix. Urban expansion and rural urbanization have created peri-urban zones, which still can harbor natural habitat remnants,
contributing to biological diversity and thus providing essential ecosystem services to urban and rural areas. The maintenance of such ecosystem services requires an understanding of the ecological processes in the ecosystem. A prerequisite for such an in-depth insight is the quantification of the underlying ecosystem functions. The ecosystem function pest control, a trophic interaction between insectivorous birds and herbivorous arthropods, was quantified in an empirical study using artificial caterpillars as prey models. This technique allows the identification of predator groups and the assessment of their predation rates. A total of 888 plasticine caterpillars were distributed at eight sites in secondary forest fragments surrounding the university campus of the federal university of São Carlos (UFScar) in peri-urban Sorocaba, southeastern Brazil. In sixteen point counts, 72 insect-eating birds, belonging to 19 species, were identified as possible artificial caterpillar attackers. Local habitat variables were measured to describe the forest vegetation structure and the landscape context. The study aimed to assess which structural components of the
forest fragments, together with the recorded bird community variables (abundance, richness, αdiversity), best explain the estimated predation rates by birds. The mean predation rate for birds was 8.25 ± 6.3 % for a reference period of eight days, representing the first quantification of the ecosystem function pest control for the study area. The three treatments of caterpillar placement heights (ground, stem: 0.5 -1.0 m, leaf: 1.5 - 2.0 m) were the best and only estimator to explain bird
predation rates. The little dense understory and ground vegetation might have facilitated the accessibility of artificial caterpillars, especially for carnivorous arthropods and birds. The detected contrast in their foraging and predation patterns suggests that arthropods and birds complement each other in their function of pest control. Bird predation rates were found to be negatively related to the vegetation structure. Thus, more open habitats, with less understory and low tree density, but high canopy cover and including dead trees were correlated with the highest predation rates and also exhibited more specialized forest-dependent bird species. This study confirms the importance of the maintenance of forest fragments in peri-urban areas, even if they are small, to preserve forest-associated birds, to contribute to the biological diversity on a broader scale, and to prevent the loss of ecosystem functions and services, mitigating some of the adverse effects of urbanization. Further investigation of the effect among the three treatments of caterpillar
placement on the predation rates is encouraged, including comparative studies among different habitat types. For future studies, it is recommended to model the avian community variables with the vegetation structure measures to predict habitat preferences of insectivorous birds. Therefore, the sampling of more units and on a bigger scale, including over a more extended period, is necessary to improve the robustness of the results, which could provide the basis for a monetary analysis of the ecosystem service pest control by birds.
3d printing is capable of providing dose individualization for pediatric medicines and translating the precision medicine approach into practical application. In pediatrics, dose individualization and preparation of small dosage forms is a requirement for successful therapy, which is frequently not possible due to the lack of suitable dosage forms. For precision medicine, individual characteristics of patients are considered for the selection of the best possible API in the most suitable dose with the most effective release profile to improve therapeutic outcome. 3d printing is inherently suitable for manufacturing of individualized medicines with varying dosages, sizes, release profiles and drug combinations in small batch sizes, which cannot be manufactured with traditional technologies. However, understanding of critical quality attributes and process parameters still needs to be significantly improved for this new technology. To ensure health and safety of patients, cleaning and process validation needs to be established. Additionally, adequate analytical methods for the in-process control of intermediates, regarding their printability as well as control of the final 3d printed tablets considering any risk of this new technology will be required. The PolyPrint consortium is actively working on developing novel polymers for fused deposition modeling (FDM) 3d printing, filament formulation and manufacturing development as well as optimization of the printing process, and the design of a GMP-capable FDM 3d printer. In this manuscript, the consortium shares its views on quality aspects and measures for 3d printing from drug-loaded filaments, including formulation development, the printing process, and the printed dosage forms. Additionally, engineering approaches for quality assurance during the printing process and for the final dosage form will be presented together with considerations for a GMP-capable printer design.
Pseudozyma antarctica Lipase B catalyzed esterification and transesterification in deep eutectic solvents (DES) was investigated in reaction systems with alcohols of different polarity. Coconut oil and crude biodiesel were deacidified successfully with non-immobilized CALBL and final acid values of 1.2 for biodiesel and 0.5 for coconut oil were obtained, while no esterification with ethanol was observed without DES. Water depletion of the lipid phase in the presence of water adsorbing DES causes this difference. Analysis of water contents revealed a 10 fold lower water content of the lipid phase in the presence of a second DES phase than in trials without utilization of DES. In contrast reactions of hydrophilic polyols are suppressed in the presence of DES. While the esterification of fructose and the transesterification with glycerol worked well in the polar solvent 2-methyl-2-butanol, almost no fructose esterification and a decreased transesterification with glycerol were observed in the presence of DES. Analysis of logP values of the substrates explains the substrate dependent differences in reactivity. The polar alcohols are probably bound strongly in the hydrogen-bonding network of the DES phase and are thus not available for lipase catalyzed reactions.
Before transporting the landfill leachate to municipal wastewater treatment plant it has to be treated in a landfill leachate treatment plant, as it comprises high concentrations of ammonium. The elimination of ammonium load in the leachate is usually done by the combined processes of nitrification and denitrification with a specially adapted biocenosis in the activated sludge (AS). For each of the steps, specialized bacteria such as Nitrosomonas, Nitrobacter and Paracoccus are used to transfer the ammonia to gaseous nitrogen. The aim of this investigation was to find suitable process parameters for a complementary treatment of fermentation water from a biogas plant together with landfill leachate. The processed water of the biogas plant consists of a higher concentration of ammonium and carbon sources or easily degradable volatile fatty acids. It can save the usage of external carbon source (acetic acid) and additionally it could also compensate the missing volumes of leachate in times of low rain and low leachate flows. To maintain the high workload for the existing leachate treatment pilot plant (LTPP), a combined treatment of landfill leachate and process water is also of economic and of ecological interest. The long-term adaption process of the biocenosis needs to be done step-by-step. Innovative process monitoring is needed to prevent biocenosis collapse. In our study, we present our set-up, a closer look at the ongoing experiment and the long-term changes in the biocenosis.
Despite great efforts to develop a vaccine against human immunodeficiency virus (HIV), which causes AIDS if untreated, no approved HIV vaccine is available to date. A promising class of vaccines are virus-like particles (VLPs), which were shown to be very effective for the prevention of other diseases. In this study, production of HI-VLPs using different 293F cell lines, followed by a three-step purification of HI-VLPs, was conducted. The quality-by-design-based process development was supported by process analytical technology (PAT). The HI-VLP concentration increased 12.5-fold while >80% purity was achieved. This article reports on the first general process development and optimization up to purification. Further research will focus on process development for polishing and formulation up to lyophilization. In addition, process analytical technology and process modeling for process automation and optimization by digital twins in the context of quality-by-design framework will be developed.
The 11th Annual Meeting of the Sponsoring Group Reinsurance (Förderkreis
Rückversicherung) on the topic of reinsurance was held 13 July 2018, in
Niederkassel near Cologne. Some 85 invited representatives of the (re)insurance
companies supporting the Sponsoring Group took part in the meeting, together with
guests. Offered for the fourth time as part of the Annual Meeting, the Researchers’
Corner gave eight members of academic staff at the Cologne Research Centre for
Reinsurance an opportunity to deliver a presentation on their respective individual
research projects.
Professor Materne also conducted interviews with Dr. Falk Niehörster (Climate Risk
Innovations) and Dr. Magnus Kobel (YAS.life). Dr. Niehörster reported on his
research and consulting activities in regard to maritime climate change and Dr. Kobel
on the business model of his InsurTec, YAS.life, and his general experience in the
establishment and development of start-ups.
In three sessions – each with 2-3 parallel lectures with posters – the most important
results of the scientific studies by the Cologne Research Centre for Reinsurance were
presented and discussed. The heterogeneity of the topics presented by academic
staff reflects the dovetailing of research theory with practice.
The 16th Annual Meeting of the Sponsoring Group Reinsurance [Förderkreis Rückversicherung] was held 16 June 2023 in Niederkassel, near Cologne. Some 90 representatives of the (re)insurance companies involved in the Sponsoring Group
took part in the meeting, along with guests. Offered for the ninth time as part of the Annual Meeting, the Researchers’ Corner gave the six academic researchers at the Cologne Research Centre for Reinsurance an opportunity to deliver a presentation on the research project in which each is involved in 2023. Over the course of three sessions, the most important results of the scientific studies by the Cologne Research Centre for Reinsurance were presented and discussed.
The heterogeneity of the topics presented reflects the dovetailing of Cologne Research Centre with reinsurance practice.
The 15th Annual Meeting of the Sponsoring Group Reinsurance [Förderkreis Rückversicherung] was held 24 June 2022. As a result of the COVID-19 pandemic, the event was held in online format again this year. Some 110 representatives of the (re)insurance companies involved in the Sponsoring Group took part in the meeting, along with guests. Offered for the eighth time as part of the Annual Meeting, the Researchers’ Corner gave the seven academic researchers at the Cologne Research Centre for Reinsurance an opportunity to deliver a presentation on the research project in which each is involved in 2022.
Over the course of three sessions, the most important results of the scientific studies by the Cologne Research Centre for Reinsurance were presented and discussed. The heterogeneity of the topics presented reflects the dovetailing of the Cologne Research Centre with reinsurance practice.
Session 1
a) Erik Winkler (LL. B.): Insurance Capital Standard (ICS)
b) Lihong Wang (M.Sc., FCII): Developments in Chinese Online Insurance 2022
c) Jörg Dirks (M.Sc., FCII): Retrocession within an ESG-compliant business orientation
Session 2
a) Robert Joniec (M.Sc., FCII, cand. PhD): Classic reinsurance placements and auctions – We know that we know nothing
b) Wolfgang Koch (M.Sc., FCII): Accounting for climate-change scenarios in the ORSA
Session 3
a) Frank Cremer (M.Sc., FCII, cand. PhD): Limits of (re)insurance cover – An analysis of exclusions of cyber-conditions
b) Fabian Lassen (M.Sc., FCII): ESG criteria in reinsurer underwriting
With the publication series, ‘Proceedings of the Researchers’ Corner’, the Cologne Research Centre for Reinsurance meets the desire for publication of the research results of our researchers along with the related discussions. The titles are reproduced in keeping with the above agenda of the Researchers’ Corner for the 15th Annual Meeting of the Sponsoring Group Reinsurance.
We would like to express our deep gratitude to the sponsors with whose assistance the activities of the Cologne Research Centre for Reinsurance, and the Annual Meeting of the Sponsoring Group Reinsurance in particular, are possible.
The 14th Annual Meeting of the Sponsoring Group Reinsurance was held 25 June 2021. Due to COVID-19, the event was held in an online format again this year. Some 80 representatives of the (re)insurance companies involved in the Sponsoring Group
took part in the meeting, along with guests. Offered for the seventh time as part of the Annual Meeting, the Researchers’ Corner gave the seven academic researchers at the Cologne Research Centre for Reinsurance an opportunity to deliver a
presentation on the research project in which each is involved in 2021. Over the course of three sessions, the most important results of the scientific studies by the Cologne Research Centre for Reinsurance were presented and discussed.
The heterogeneity of the topics presented reflects the dovetailing of Cologne Research Centre with reinsurance practice.
The 13th Annual Meeting of the Sponsoring Group Reinsurance was held 26 June 2020. Due to COVID-19, the event was held online this year. Some 80 representatives of the (re)insurance companies involved in the Sponsoring Group took part in the meeting, along with guests. Offered for the sixth time as part of the Annual Meeting, the Researchers’ Corner gave the seven academic researchers at the Cologne Research Centre for Reinsurance an opportunity to deliver a presentation on the research project each in which each is involved in 2020.
In three sessions – each featuring 2-3 parallel lectures with posters – the most important results of the scientific studies by the Cologne Research Centre for
Reinsurance were presented and discussed. The heterogeneity of the topics
presented by academic staff reflects the dovetailing of Cologne Research Centre with reinsurance practice.
Session 1
a) Manuel Dietmann (M.Sc.): Preventive recovery planning for insurance companies
b) Robert Joniec (M.Sc., FCII, cand. PhD): Capital is fungible, the market is
growing more efficient – But how valid are research results?
c) Jörg Dirks (M.Sc., FCII): Cyber risks in reinsurance – Insurable on a parametric basis through AI?
Session 2
a) Wolfgang Koch (M.Sc., FCII): Trend in sovereign cat pools in emerging and developing economies
b) Fabian Lassen (M.Sc., FCII): Environmental social governance – A look at reinsurers
Session 3
a) Fabian Pütz (M.Sc., PhD): Reinsurance aspects of product recalls in the automobile sector
b) Lihong Wang (M.Sc., FCII): China’s Belt and Road Initiative (BRI) – Its impact
on the global (re)insurance industry
Poster session
a) Fabian Lassen (M.Sc., FCII): Private-public partnership – The solution for the insurability of pandemics?
b) Christian Serries (B.Sc.): Silent Cyber as a challenge for the (re-)
insurance industry
c) Frank Cremer (B.Sc. / FCII): Digital ecosystems – Relevance for reinsurance?
d) Harald Kurtze (B.Sc.): Sharing economy – Impacts for reinsurance?
With the publication series, ‘Proceedings of the Researchers’ Corner’, the Cologne Research Centre for Reinsurance meets the desire for publication of the research results of our scholars together with the accompanying posters and discussions. The titles are reproduced in keeping with the above agenda of the Researchers’ Corner
for the 13th Annual Meeting of the Förderkreis Rückversicherung [Sponsoring Group Reinsurance].
The 12th Annual Meeting of the Sponsoring Group Reinsurance [Förderkreis Rückversicherung] was held 5th July 2019 in Niederkassel, near Cologne. Some 80
representatives of the (re)insurance companies involved in the Sponsoring Group took part in the meeting, along with guests. Offered for the fifth time as part of the
Annual Meeting, the Researchers’ Corner gave eight members of academic staff at the Cologne Research Centre for Reinsurance an opportunity to deliver a presentation on their respective current research projects. In three sessions – each featuring 2-3 parallel lectures with posters – the most important results of the scientific studies by the Cologne Research Centre for Reinsurance were presented and discussed. The heterogeneity of the topics presented by academic staff reflects the dovetailing of Cologne Research Centre with reinsurance practice.
Session 1
a) Manuel Dietmann (M.Sc.): The increasing importance of the riskmanagement function in insurance companies
b) Robert Joniec (M.Sc., FCII, cand. PhD): How is the reinsurance cycle doing?
c) Wolfgang Koch (M.Sc., FCII): Information asymmetries between reinsurance brokers and assignors
Session 2
a) Jörg Dirks (M.Sc., FCII): Unmanned aircraft – Evolution of the market for aviation (re-)insurance
b) Fabian Lassen (M.Sc., FCII): Reducing volatility through use of an insurance swap
c) Fabian Pütz (M.Sc., cand. PhD): Transferring cat risks from emerging markets from a macroeconomic perspective Session 3
a) Kai-Olaf Knocks (M.A., FCII): The ILS market in 2019 – discouragement or wait-and-see?
b) Lihong Wang (M.Sc., FCII, cand. PhD): China InsurTech development
With the publication series, ‘Proceedings of the Researchers’ Corner’, the Cologne Research Centre for Reinsurance meets the desire for publication of the research results of our scholars together with the accompanying posters and discussions. The titles are reproduced in keeping with the above agenda of the Researchers’ Corner for the 12th Annual Meeting of the Sponsoring Group Reinsurance. As part of the event, Prof. Materne also conducted an interview with Mr Ingo Wichelhaus (Senior Director, Mount Street) on the topic of risk management and portfolio management. Particular attention was devoted to the broad spectrum of risk for financing in the shipping sector.
The 10th Annual Meeting of the Sponsoring Group Reinsurance was held 7 July 2017, in Niederkassel
near Köln. Some 80 representatives of the (re)insurance companies involved in the Sponsoring Group took part in the meeting, together with invited guests. Offered for the third time as part of the Annual Meeting, the Researchers’ Corner gave nine members of academic staff at the Cologne Research Centre for Reinsurance an opportunity to deliver short presentations on their individual research projects. Professor Materne also conducted interviews with Messrs Lorenz Kielwein and
Frank Baumann. Kielwein reported on the application of mathematical systems theory to processes in change management, and Baumann on his 30 years of experience at Gothaer. During each of three sessions, three short lectures with posters were held in parallel and discussed afterwards. The heterogeneity of the topics presented by the staff members reflects the dovetailing
of research theory with practice.
In the sessions, the following speakers presented in German and English:
Round 1
a) Fabian Pütz (M.Sc.)
Alternative Capital and Basic Risk in the Standard Formula (Non-Life) of Solvency II
b) Manuel Dietmann (M.Sc.)
SFCR: Findings for Initial Publication
c) Jan Böggemann (B.Sc.)
Optimising the Purchase of Optional Reinsurance by an Industrial Insurer
Round 2
a) Robert Joniec (M.Sc.)
Actuarial swap
b) Lucas Kaiser (M.Sc.)
The Impact of Different Determinants on the Rating of Reinsurance Companies
c) Lihong Wang (M.Sc., FCII)
Chinese Automobile Vehicle Recall Insurance
Round 3
a) Sebastian Hoos (M.Sc., FCII)
Critical Analysis of the Practical Application of the Definition of an Event
b) Fabian Lassen (B.A.)
Employees in the Reinsurance Industry: Germany and the USA.
c) Kai-Olaf Knocks (M.A., FCII)
[Autonomous Driving: Evolution or Revolution?
The presentations also featured the work of another member of our staff who unfortunately, for
logistical reasons, was able to present his research project in poster form but was not able to deliver
a brief lecture.
Poster
d) Wolfgang Koch (B.A.)
Public-Private Partnership in Emerging and Developing Countries.
We would like to thank the funding bodies who make this event possible to begin with and provide our scholars an opportunity to conduct their research.