C. Computer Systems Organization
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Observational studies and clinical trials have become increasingly important over recent years and play an essential role in advancing medical knowledge. In today’s world of clinical research, it is not possible to imagine trials without the founda-tion of a well-established it-infrastructure. Electronic capture and usage of data is pervasive.
In practice, medical progress requires the ability to integrate data from different systems. An essential factor in enabling different actors, such as institutions and hospitals, to have their systems exchange structured data and make use of the information is the interoperability of the data and systems.
FHIR (Fast Healthcare Interoperable Resources) is a free and easily customizable HL7 platform standard, based on 30 years of experience of HL7. It is focused on providing health-related information and defines a set of capabilities used in the health care process.
This thesis will provide a conceptual approach for working with FHIR, as well as concrete approaches for working with FHIR profiles and for customizing the standard for particular use cases. It will be carried out in cooperation with the Medical Systems R&D, which is a service provider within the University Hospital of Cologne.
The guiding request approach will focus on the evaluation of requirements for clini-cal trials and how clinical research protocols can be represented in an interoperable and machine-parsable format using FHIR.
REST became the go to approach when it comes to large scale distributed systems on, or outside the World Wide Web. This paper aims to give a brief overview of what REST is and what its main draws and benefits are. Secondly, I will showcase the implementation of REST using HTTP and why this approach became as popular as it is today. Based on my research I concluded that REST’s advantages in scalability, coupling, performance and its seamless integration with HTTP enabled it to rightfully overtake classic RPC based approaches.